Substance Details

CAS Registry Number: 189261-10-7

CA Index Name: Immunoglobulin G4, anti-(human integrin α4) (human-mouse monoclonal AN100226 γ4-chain), disulfide with human-mouse monoclonal AN100226 light chain, dimer


Sequence Strand: 1326, 450, 450, 213, 213
1:  QVQLVQSGAE VKKPGASVKV SCKASGFNIK DTYIHWVRQA PGQRLEWMGR
51:  IDPANGYTKY DPKFQGRVTI TADTSASTAY MELSSLRSED TAVYYCAREG
101:  YYGNYGVYAM DYWGQGTLVT VSSASTKGPS VFPLAPCSRS TSESTAALGC
151:  LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG
201:  TKTYTCNVDH KPSNTKVDKR VESKYGPPCP SCPAPEFLGG PSVFLFPPKP
251:  KDTLMISRTP EVTCVVVDVS QEDPEVQFNW YVDGVEVHNA KTKPREEQFN
301:  STYRVVSVLT VLHQDWLNGK EYKCKVSNKG LPSSIEKTIS KAKGQPREPQ
351:  VYTLPPSQEE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV
401:  LDSDGSFFLY SRLTVDKSRW QEGNVFSCSV MHEALHNHYT QKSLSLSLGK

1:  QVQLVQSGAE VKKPGASVKV SCKASGFNIK DTYIHWVRQA PGQRLEWMGR
51:  IDPANGYTKY DPKFQGRVTI TADTSASTAY MELSSLRSED TAVYYCAREG
101:  YYGNYGVYAM DYWGQGTLVT VSSASTKGPS VFPLAPCSRS TSESTAALGC
151:  LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG
201:  TKTYTCNVDH KPSNTKVDKR VESKYGPPCP SCPAPEFLGG PSVFLFPPKP
251:  KDTLMISRTP EVTCVVVDVS QEDPEVQFNW YVDGVEVHNA KTKPREEQFN
301:  STYRVVSVLT VLHQDWLNGK EYKCKVSNKG LPSSIEKTIS KAKGQPREPQ
351:  VYTLPPSQEE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV
401:  LDSDGSFFLY SRLTVDKSRW QEGNVFSCSV MHEALHNHYT QKSLSLSLGK

1:  DIQMTQSPSS LSASVGDRVT ITCKTSQDIN KYMAWYQQTP GKAPRLLIHY
51:  TSALQPGIPS RFSGSGSGRD YTFTISSLQP EDIATYYCLQ YDNLWTFGQG
101:  TKVEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD
151:  NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL
201:  SSPVTKSFNR GEC

1:  DIQMTQSPSS LSASVGDRVT ITCKTSQDIN KYMAWYQQTP GKAPRLLIHY
51:  TSALQPGIPS RFSGSGSGRD YTFTISSLQP EDIATYYCLQ YDNLWTFGQG
101:  TKVEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD
151:  NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL
201:  SSPVTKSFNR GEC


Sequence Notes:
Type Location Description
bridge CYS-96 CYS-22 disulfide bridge
bridge CYS-137 CYS-213'' disulfide bridge
bridge CYS-206 CYS-150 disulfide bridge
bridge CYS-229 CYS-229' disulfide bridge
bridge CYS-232 CYS-232' disulfide bridge
bridge CYS-324 CYS-264 disulfide bridge
bridge CYS-428 CYS-370 disulfide bridge
bridge CYS-96' CYS-22' disulfide bridge
bridge CYS-137' CYS-213''' disulfide bridge
bridge CYS-206' CYS-150' disulfide bridge
bridge CYS-324' CYS-264' disulfide bridge
bridge CYS-428' CYS-370' disulfide bridge
bridge CYS-88'' CYS-23'' disulfide bridge
bridge CYS-193'' CYS-133'' disulfide bridge
bridge CYS-88''' CYS-23''' disulfide bridge
bridge CYS-193''' CYS-133''' disulfide bridge


Chemical Structure:

189261-10-7:Immunoglobulin G4, anti-(human integrin α4) (human-mouse monoclonal AN100226 γ4-chain), disulfide with human-mouse monoclonal AN100226 light chain, dimer

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