Substance Details

CAS Registry Number: 216503-57-0

CA Index Name: Immunoglobulin G1, anti-(human CD52 (antigen)) (human-rat monoclonal CAMPATH-1H γ1-chain), disulfide with human-rat monoclonal CAMPATH-1H light chain, dimer


Sequence Strand: 1330, 451, 451, 214, 214
1:  QVQLQESGPG LVRPSQTLSL TCTVSGFTFT DFYMNWVRQP PGRGLEWIGF
51:  IRDKAKGYTT EYNPSVKGRV TMLVDTSKNQ FSLRLSSVTA ADTAVYYCAR
101:  EGHTAAPFDY WGQGSLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV
151:  KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ
201:  TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
251:  PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY
301:  NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP
351:  QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP
401:  VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG
451:  K

1:  QVQLQESGPG LVRPSQTLSL TCTVSGFTFT DFYMNWVRQP PGRGLEWIGF
51:  IRDKAKGYTT EYNPSVKGRV TMLVDTSKNQ FSLRLSSVTA ADTAVYYCAR
101:  EGHTAAPFDY WGQGSLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV
151:  KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ
201:  TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
251:  PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY
301:  NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP
351:  QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP
401:  VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG
451:  K

1:  DIQMTQSPSS LSASVGDRVT ITCKASQNID KYLNWYQQKP GKAPKLLIYN
51:  TNNLQTGVPS RFSGSGSGTD FTFTISSLQP EDIATYYCLQ HISRPRTFGQ
101:  GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV
151:  DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG
201:  LSSPVTKSFN RGEC

1:  DIQMTQSPSS LSASVGDRVT ITCKASQNID KYLNWYQQKP GKAPKLLIYN
51:  TNNLQTGVPS RFSGSGSGTD FTFTISSLQP EDIATYYCLQ HISRPRTFGQ
101:  GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV
151:  DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG
201:  LSSPVTKSFN RGEC


Sequence Notes:
Type Location Description
bridge CYS-98 CYS-22 disulfide bridge
bridge CYS-204 CYS-148 disulfide bridge
bridge CYS-224 CYS-214'' disulfide bridge
bridge CYS-230 CYS-230' disulfide bridge
bridge CYS-233 CYS-233' disulfide bridge
bridge CYS-325 CYS-265 disulfide bridge
bridge CYS-429 CYS-371 disulfide bridge
bridge CYS-98' CYS-22' disulfide bridge
bridge CYS-204' CYS-148' disulfide bridge
bridge CYS-244' CYS-214''' disulfide bridge
bridge CYS-325' CYS-265' disulfide bridge
bridge CYS-249' CYS-371' disulfide bridge
bridge CYS-88'' CYS-23'' disulfide bridge
bridge CYS-194'' CYS-134'' disulfide bridge
bridge CYS-88''' CYS-23''' disulfide bridge
bridge CYS-194''' CYS-134''' disulfide bridge


Chemical Structure:

216503-57-0:Immunoglobulin G1, anti-(human CD52 (antigen)) (human-rat monoclonal CAMPATH-1H γ1-chain), disulfide with human-rat monoclonal CAMPATH-1H light chain, dimer

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