Substance Details

CAS Registry Number: 219685-50-4

CA Index Name: Immunoglobulin, anti-(human complement C5 α-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G1.1 light chain, dimer


Sequence Strand: 1728, 650, 650, 214, 214
1:  QVQLVQSGAE VKKPGASVKV SCKASGYIFS NYWIQWVRQA PGQGLEWMGE
51:  ILPGSGSTEY TENFKDRVTM TRDTSTSTVY MELSSLRSED TAVYYCARYF
101:  FGSSPNWYFD VWGQGTLVTV SSASTKGPSV FPLAPCSRST SESTAALGCL
151:  VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSNFGT
201:  QTYTCNVDHK PSNTKVDKTV GERPAQGGRV SAGSQAQPSC LDAPRLCSPS
251:  PGQQGRPHLS PHPEASARPT HAQGEGLLAF STRLQAGTGW VPLPQALHTQ
301:  GQVLGSDLPK AISGRTLPPD LSRPQGQTVH SLSSDTFLSS QIRVTPNLLS
351:  AERKCCVECP PCPGKPAQAS PSSSRRDRCP RVACIQGQPQ LGADTSTSIS
401:  SSAPPVAGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSQE DPEVQFNWYV
451:  DGVEVHNAKT KPREEQFNST DRVVSVLTVL HQDWLNGKEY KCKVSTKASR
501:  PPSRKPSPKP KVGPTGCEGH MDRGQLGPPS ALGVTAVPTS VPTGQPREPQ
551:  VYTLPPSQEE MTKNQVSLTC LVKGLYPSDI AVEWESNGQP ENNYKTTPPV
601:  LDSDGSFFLY SRLTVDKSRW QEGNVFSCSV MHEALHNHYT QKSLSLSLGK

1:  QVQLVQSGAE VKKPGASVKV SCKASGYIFS NYWIQWVRQA PGQGLEWMGE
51:  ILPGSGSTEY TENFKDRVTM TRDTSTSTVY MELSSLRSED TAVYYCARYF
101:  FGSSPNWYFD VWGQGTLVTV SSASTKGPSV FPLAPCSRST SESTAALGCL
151:  VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSNFGT
201:  QTYTCNVDHK PSNTKVDKTV GERPAQGGRV SAGSQAQPSC LDAPRLCSPS
251:  PGQQGRPHLS PHPEASARPT HAQGEGLLAF STRLQAGTGW VPLPQALHTQ
301:  GQVLGSDLPK AISGRTLPPD LSRPQGQTVH SLSSDTFLSS QIRVTPNLLS
351:  AERKCCVECP PCPGKPAQAS PSSSRRDRCP RVACIQGQPQ LGADTSTSIS
401:  SSAPPVAGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSQE DPEVQFNWYV
451:  DGVEVHNAKT KPREEQFNST DRVVSVLTVL HQDWLNGKEY KCKVSTKASR
501:  PPSRKPSPKP KVGPTGCEGH MDRGQLGPPS ALGVTAVPTS VPTGQPREPQ
551:  VYTLPPSQEE MTKNQVSLTC LVKGLYPSDI AVEWESNGQP ENNYKTTPPV
601:  LDSDGSFFLY SRLTVDKSRW QEGNVFSCSV MHEALHNHYT QKSLSLSLGK

1:  DIQMTQSPSS LSASVGDRVT ITCGASENIY GALNWYQRKP GKAPKLLIYG
51:  ATNLADGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQN VLNTPLTFGQ
101:  GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV
151:  DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG
201:  LSSPVTKSFN RGEC

1:  DIQMTQSPSS LSASVGDRVT ITCGASENIY GALNWYQRKP GKAPKLLIYG
51:  ATNLADGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQN VLNTPLTFGQ
101:  GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV
151:  DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG
201:  LSSPVTKSFN RGEC


Sequence Notes:
Type Location Description
bridge CYS-96 CYS-22 disulfide bridge
bridge CYS-205 CYS-149 disulfide bridge
bridge CYS-96' CYS-22' disulfide bridge
bridge CYS-205' CYS-149' disulfide bridge
bridge CYS-88'' CYS-23'' disulfide bridge
bridge CYS-194'' CYS-134'' disulfide bridge
bridge CYS-136 CYS-214'' disulfide bridge
bridge CYS-88''' CYS-23''' disulfide bridge
bridge CYS-194''' CYS-134''' disulfide bridge
bridge CYS-136' CYS-214''' disulfide bridge
bridge CYS-240 CYS-240' disulfide bridge
bridge CYS-247 CYS-247' disulfide bridge


Chemical Structure:

219685-50-4:Immunoglobulin, anti-(human complement C5 α-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide with human-mouse monoclonal 5G1.1 light chain, dimer

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