Substance Details

CAS Registry Number: 242138-07-4

CA Index Name: Immunoglobulin G1, anti-(human immunoglobulin E Fc region) (human-mouse monoclonal E25 clone pSVIE25 γ-chain), disulfide with human-mouse monoclonal E25 clone pSVIE25 κ-chain, dimer


Sequence Strand: 1338, 451, 451, 218, 218
1:  EVQLVESGGG LVQPGGSLRL SCAVSGYSIT SGYSWNWIRQ APGKGLEWVA
51:  SITYDGSTNY NPSVKGRITI SRDDSKNTFY LQMNSLRAED TAVYYCARGS
101:  HYFGHWHFAV WGQGTLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV
151:  KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ
201:  TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
251:  PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY
301:  NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP
351:  QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP
401:  VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG
451:  K

1:  EVQLVESGGG LVQPGGSLRL SCAVSGYSIT SGYSWNWIRQ APGKGLEWVA
51:  SITYDGSTNY NPSVKGRITI SRDDSKNTFY LQMNSLRAED TAVYYCARGS
101:  HYFGHWHFAV WGQGTLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV
151:  KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ
201:  TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
251:  PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY
301:  NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP
351:  QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP
401:  VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG
451:  K

1:  DIQLTQSPSS LSASVGDRVT ITCRASQSVD YDGDSYMNWY QQKPGKAPKL
51:  LIYAASYLES GVPSRFSGSG SGTDFTLTIS SLQPEDFATY YCQQSHEDPY
101:  TFGQGTKVEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV
151:  QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV
201:  THQGLSSPVT KSFNRGEC

1:  DIQLTQSPSS LSASVGDRVT ITCRASQSVD YDGDSYMNWY QQKPGKAPKL
51:  LIYAASYLES GVPSRFSGSG SGTDFTLTIS SLQPEDFATY YCQQSHEDPY
101:  TFGQGTKVEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV
151:  QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV
201:  THQGLSSPVT KSFNRGEC


Sequence Notes:
Type Location Description
bridge CYS-96 CYS-22 disulfide bridge
bridge CYS-204 CYS-148 disulfide bridge
bridge CYS-325 CYS-265 disulfide bridge
bridge CYS-429 CYS-371 disulfide bridge
bridge CYS-96' CYS-22' disulfide bridge
bridge CYS-204' CYS-148' disulfide bridge
bridge CYS-326' CYS-265' disulfide bridge
bridge CYS-429' CYS-371' disulfide bridge
bridge CYS-92'' CYS-23'' disulfide bridge
bridge CYS-198'' CYS-138'' disulfide bridge
bridge CYS-92''' CYS-23''' disulfide bridge
bridge CYS-198''' CYS-138''' disulfide bridge
bridge CYS-230 CYS-230' disulfide bridge
bridge CYS-233 CYS-233' disulfide bridge
bridge CYS-224 CYS-218'' disulfide bridge
bridge CYS-224' CYS-218''' disulfide bridge


Chemical Structure:

242138-07-4:Immunoglobulin G1, anti-(human immunoglobulin E Fc region) (human-mouse monoclonal E25 clone pSVIE25 γ-chain), disulfide with human-mouse monoclonal E25 clone pSVIE25 κ-chain, dimer

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