Substance Details

CAS Registry Number: 347396-82-1

CA Index Name: Immunoglobulin G1, anti-(human vascular endothelial growth factor) Fab fragment (human-mouse monoclonal rhuFAb V2 γ1-chain), disulfide with human-mouse monoclonal rhuFAb V2 light chain


Sequence Strand: 445, 231, 214
1:  EVQLVESGGG LVQPGGSLRL SCAASGYDFT HYGMNWVRQA PGKGLEWVGW
51:  INTYTGEPTY AADFKRRFTF SLDTSKSTAY LQMNSLRAED TAVYYCAKYP
101:  YYYGTSHWYF DVWGQGTLVT VSSASTKGPS VFPLAPSSKS TSGGTAALGC
151:  LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG
201:  TQTYICNVNH KPSNTKVDKK VEPKSCDKTH L

1:  DIQLTQSPSS LSASVGDRVT ITCSASQDIS NYLNWYQQKP GKAPKVLIYF
51:  TSSLHSGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQQ YSTVPWTFGQ
101:  GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV
151:  DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG
201:  LSSPVTKSFN RGEC


Sequence Notes:
Type Location Description
bridge CYS-96 CYS-22 disulfide bridge
bridge CYS-206 CYS-150 disulfide bridge
bridge CYS-88' CYS-23' disulfide bridge
bridge CYS-194' CYS-134' disulfide bridge
bridge CYS-226 CYS-214' disulfide bridge


Chemical Structure:

347396-82-1:Immunoglobulin G1, anti-(human vascular endothelial growth factor) Fab fragment (human-mouse monoclonal rhuFAb V2 γ1-chain), disulfide with human-mouse monoclonal rhuFAb V2 light chain

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